USP-S | Orange Anolis appeared in CS:GO on September 22, 2021. The skin is part of The 2021 Dust 2 Collection, dedicated to the eponymous map and containing 19 weapon finishes. It was introduced to the shooter along with Operation Riptide.

The skin mimics the coloration of the iguanid lizard belonging to the Anolis genus, native to both Americas. That’s why the gun's surface is covered with a large number of spots of different shapes and sizes. The skin's color palette consists of shades of yellow and red.

The pattern index determines the appearance of the picture formed. There are no valuable pattern variations for this skin.

Float Value of USP-S | Orange Anolis can vary between 0.00 and 0.37, allowing the skin to be obtainable in any exterior quality category except for the last two. As the float value increases, the weapon gradually darkens and loses some of its paint. With heavy wear, about a quarter of all paint is erased.

USP-S | Orange Anolis belongs to the “Restricted” rarity grade and is available in a souvenir version. The skin is moderately popular among CS2 players.